The postnatal methylation of transfer ribonucleic acid in brain. Evidence for the methylation of precursor transfer ribonucleic acid.

Indirect evidence for the presence of Ribonucleic acid in vesicular stomatitis Virions

Differences in the Methylation of Transfer Ribonucleic Acid in VVitro by the Mitochondrial and Cytoplasmic Transfer Ribonucleic Acid Methylases of HeLa Cells

The methylation of Escherichia coli B transfer RNA in vitro by HeLa mitochondrial and cytoplasmic extracts was examined. The following differences were found. (a) The cytoplasmic extract methylated E. coli B tRNA to a much greater extent than did the mitochondrial extract. (b) The two extracts methylated different sites on E. coli B tRNA, thereby generating different methylated oligonucleotide ...

Differences in the Methylation of Transfer Ribonucleic Acid in VVitro by the Mitochondrial and Cytoplasmic Transfer Ribonucleic Acid Methylases of HeLa Cells

The methylation of Escherichia coli B transfer RNA in vitro by HeLa mitochondrial and cytoplasmic extracts was examined. The following differences were found. (a) The cytoplasmic extract methylated E. coli B tRNA to a much greater extent than did the mitochondrial extract. (b) The two extracts methylated different sites on E. coli B tRNA, thereby generating different methylated oligonucleotide ...

The Methylation of Transfer Ribonucleic Acid during Regeneration of the Liver

Transfer ribonucleic acid(1) is methylated after the molecule is synthesized; at least eight enzymes are involved in the transfer of methyl groups (derived from methionine). The time courses of methylation and synthesis of tRNA during rat liver regeneration have been compared in an in vivo radioisotopic study, using 6-orotic acid-(14)C and (3)H-methyl-L-methionine as precursors in double label ...

Foot-and-mouth disease virus-induced alterations of baby hamster kidney cell macromolecular biosynthesis: inhibition of ribonucleic acid methylation and stimulation of ribonucleic acid synthesis.

The kinetics of ribonucleic acid (RNA) and protein synthesis and RNA methylation were examined after foot-and-mouth disease virus (FMDV) infection of baby hamster kidney cells. The synthesis of RNA extracted from the whole cells was stimulated two- to threefold above the control level of synthesis. This increased rate was attributed to viral RNA synthesis. The inhibition of host RNA methylation...